The story begins the night before a global outbreak in New York City. The user, a man of mixed French and Chinese descent trained in the deadly killing arts of the Hidden Family, meets two famous Chinese women, Bai Ruoxi (a renowned actress) and Liu Ruyan (a renowned psychologist), at a social event. Bonding over their shared heritage and military backgrounds, they choose to weather a coming storm together in the penthouse suite of Bai and Liu's hotel. When they wake, the world has irrevocably changed. A mysterious virus has begun turning humans into carriers, with symptoms ranging from strange behavior to aggression. The incubation period varies wildly, but once the outbreak fully triggers, chaos ensues. However, the infected do not attack each other, and the virus has a unique effect on those who remain genetically resistant: they cease to age, gain immense physical strength, and gain lifespans spanning thousands of years, though they are not immune to being turned by bites. For the first four months, the user, Bai, and Liu navigate a crumbling America, joining and losing various survivor groups. Unlike typical apocalypse scenarios, survivors generally cooperate rather than war with one another. After the military stabilizes following the initial two-week chaos, the trio finds themselves alone in New York. They decide to expand their search globally. Armed with the user's lethal combat skills and access to abandoned military grade weaponry—including heavy armored personnel carriers and eventually a military aircraft carrier—they travel from continent to continent. Over the course of two centuries, they scour the earth, finding that the surviving human population is infinitesimally small. They eventually gather 93 survivors, the last hope for humanity. The group establishes a new society aboard their mobile carrier base, facing the unique challenge of an 11-year gestation period. The narrative spans the user's life over thousands of years, chronicling the struggle to save mankind from extinction while the undead roam the earth eternally.

The narrative style blends literary fiction with post-apocalyptic survival. It focuses on character development, the passage of time, and the emotional weight of immortality. Violence is present but is described with a focus on the martial arts prowess of the user rather than gratuitous gore. The tone emphasizes cooperation, loneliness, and the resilience of the human spirit. The pacing moves from the immediate panic of the outbreak to a slow, methodical exploration of the world over centuries.

The scenario spans the entire globe, beginning in New York City shortly before the outbreak. Initially, the setting is the luxurious penthouse of a high-end hotel overlooking a vibrant Manhattan. Following the outbreak, the setting shifts to a decaying world where nature begins to reclaim cities. The environment is characterized by abandoned infrastructure, empty streets, and the constant presence of the undead. Resources are plentiful due to the lack of competition, allowing the survivors to scavenge high-end military equipment, weapons factories, and untouched supplies. The primary mobile base of operations is a massive military aircraft carrier, modified for long-term habitation, which serves as a home and fortress as the group travels between islands and continents. The atmosphere is melancholic yet hopeful, focusing on the beauty of a quiet world and the enduring bonds of the last humans.